ADAMTS13 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comADAMTS13 Polyclonal Antibody for Human(Homo sapiens)

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ADAMTS13 (Gene name),

A disintegrin and metalloproteinase with thrombospondin motifs 13 (Protein name ), ATS13_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ADAMTS13(UNQ6102/PRO20085;C9orf8);

Protein name:

A disintegrin and metalloproteinase with thrombospondin motifs 13(ADAM-TS 13;ADAM-TS13;ADAMTS-13);

Alternative:

von Willebrand factor-cleaving protease(vWF-CP;vWF-cleaving protease);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Cleaves the vWF multimers in plasma into smaller forms.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

1427

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1427:

LRGQYWTLQS | WVPEMQDPQS | WKGKEGT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q76LX8

STRING:

9606.ENSP00000360997

UniGene:

Hs.131433

Pfam:

PF01421

SMR:

Q76LX8

MIM:

274150

KEGG:

hsa:11093

Uniprot:

Q76LX8

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ELISA Kit for Human ADAM-TS 13

Cat.:

E0950m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human ADAM-TS 13

Cat.:

E0950h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human ADAM-TS 13

Cat.:

U0950h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human ADAM-TS 13

Cat.:

U0950m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human ADAM-TS 13

Cat.:

P0950Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ADAM-TS 13

Cat.:

P0950Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human ADAM-TS 13

Protein for Human ADAM-TS 13

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A novel human metalloprotease synthesized in the liver and secreted into the blood: possibly, the von Willebrand factor-cleaving protease?"
Soejima K. , Mimura N. , Hirashima M. , Maeda H. , Hamamoto T. , Nakagaki T. , Nozaki C.
J. Biochem.130:475-480(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 75-103;TISSUE SPECIFICITY
tissue: Liver.
2.

"Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura."
Zheng X. , Chung D. , Takayama T.K. , Majerus E.M. , Sadler J.E. , Fujikawa K.
J. Biol. Chem.276:41059-41063(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);GLYCOSYLATION;VARIANT VAL-900
tissue: Liver.
3.

"Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura."
Levy G.G. , Nichols W.C. , Lian E.C. , Foroud T. , McClintick J.N. , McGee B.M. , Yang A.Y. , Siemieniak D.R. , Stark K.R. , Gruppo R. , Sarode R. , Shurin S.B. , Chandrasekaran V. , Stabler S.P. , Sabio H. , Bouhassira E.E. , Upshaw J.D. Jr. , Ginsburg D. , more...
Nature413:488-494(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INVOLVEMENT IN THROMBOTIC THROMBOCYTOPENIC PURPURA;VARIANTS TTP ASP-96; CYS-102; ILE-196; HIS-398; GLY-528; CYS-692; GLY-951; GLY-1024 AND TYR-1213;VARIANTS TRP-7; GLU-448; ALA-618; HIS-625; VAL-732; VAL-900 AND THR-1033
tissue: Liver.
4.

"Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains."
Cal S. , Obaya A.J. , Llamazares M. , Garabaya C. , Quesada V. , Lopez-Otin C.
Gene283:49-62(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3)
tissue: Liver.
5.

"Cloning of a sugar transporter gene, a G-beta subunit like gene and three novel genes in human chromosome 9q34."
Young J.M. , Woodward K.J. , Aziz S. , Burley M. , Kwiatkowski D.J. , Povey S.
Submitted (1998-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
tissue: Brain.
6.

SeattleSNPs variation discovery resource
Submitted (2006-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS TRP-7; GLU-448; HIS-456; LEU-457; ALA-618; HIS-625; LYS-740; VAL-900; ARG-982; THR-1033 AND ILE-1226
7.

"DNA sequence and analysis of human chromosome 9."
Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 275-1427;VARIANT GLU-448
10.

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S. , Weil B. , Wellenreuther R. , Gassenhuber J. , Glassl S. , Ansorge W. , Boecher M. , Bloecker H. , Bauersachs S. , Blum H. , Lauber J. , Duesterhoeft A. , Beyer A. , Koehrer K. , Strack N. , Mewes H.-W. , Ottenwaelder B. , Obermaier B. , more...
Genome Res.11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1191-1427
tissue: Testis.
11.

"Partial amino acid sequence of purified von Willebrand factor-cleaving protease."
Gerritsen H.E. , Robles R. , Laemmle B. , Furlan M.
Blood98:1654-1661(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 75-89
12.

"Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family."
Fujikawa K. , Suzuki H. , McMullen B. , Chung D.
Blood98:1662-1666(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 75-94
13.

"Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13."
Zheng X. , Nishio K. , Majerus E.M. , Sadler J.E.
J. Biol. Chem.278:30136-30141(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION;SUBCELLULAR LOCATION
14.

"Cleavage of the ADAMTS13 propeptide is not required for protease activity."
Majerus E.M. , Zheng X. , Tuley E.A. , Sadler J.E.
J. Biol. Chem.278:46643-46648(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;MUTAGENESIS OF ARG-71 AND ARG-73
15.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-614; ASN-667 AND ASN-1354
tissue: Plasma.
16.

"Zinc and calcium ions cooperatively modulate ADAMTS13 activity."
Anderson P.J. , Kokame K. , Sadler J.E.
J. Biol. Chem.281:850-857(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
17.

"O-fucosylation is required for ADAMTS13 secretion."
Ricketts L.M. , Dlugosz M. , Luther K.B. , Haltiwanger R.S. , Majerus E.M.
J. Biol. Chem.282:17014-17023(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT SER-698; SER-757; SER-907; SER-965; SER-1027 AND SER-1087;IDENTIFICATION BY MASS SPECTROMETRY;MUTAGENESIS OF SER-399; SER-698; SER-757; SER-907; SER-965; SER-1027 AND SER-1087
18.

"A functional calcium-binding site in the metalloprotease domain of ADAMTS13."
Gardner M.D. , Chion C.K. , de Groot R. , Shah A. , Crawley J.T. , Lane D.A.
Blood113:1149-1157(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;CALCIUM-BINDING SITES;MUTAGENESIS OF GLU-83; ASP-173; GLU-184; ASP-187 AND GLU-212
19.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-667 AND ASN-707
20.

"ADAMTS13 mutations and polymorphisms in congenital thrombotic thrombocytopenic purpura."
Lotta L.A. , Garagiola I. , Palla R. , Cairo A. , Peyvandi F.
Hum. Mutat.31:11-19(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
21.

"Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor."
Akiyama M. , Takeda S. , Kokame K. , Takagi J. , Miyata T.
Proc. Natl. Acad. Sci. U.S.A.106:19274-19279(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 287-685;FUNCTION;GLYCOSYLATION AT ASN-552 AND ASN-614;SPACER DOMAIN;DISULFIDE BONDS
22.

"Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity."
Kokame K. , Matsumoto M. , Soejima K. , Yagi H. , Ishizashi H. , Funato M. , Tamai H. , Konno M. , Kamide K. , Kawano Y. , Miyata T. , Fujimura Y.
Proc. Natl. Acad. Sci. U.S.A.99:11902-11907(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP PRO-268 AND TYR-508;VARIANTS GLU-448 AND SER-475;CHARACTERIZATION OF VARIANTS TTP PRO-268 AND TYR-508;CHARACTERIZATION OF VARIANTS GLU-448 AND SER-475
23.

"von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP."
Schneppenheim R. , Budde U. , Oyen F. , Angerhaus D. , Aumann V. , Drewke E. , Hassenpflug W. , Haberle J. , Kentouche K. , Kohne E. , Kurnik K. , Mueller-Wiefel D. , Obser T. , Santer R. , Sykora K.W.
Blood101:1845-1850(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP GLN-232; CYS-263 AND LEU-353
24.

"ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS13."
Antoine G. , Zimmermann K. , Plaimauer B. , Grillowitzer M. , Studt J.D. , Lammle B. , Scheiflinger F.
Br. J. Haematol.120:821-824(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP TRP-1336;VARIANT VAL-732
25.

"Mutation analysis and clinical implications of von Willebrand factor-cleaving protease deficiency."
Assink K. , Schiphorst R. , Allford S. , Karpman D. , Etzioni A. , Brichard B. , van de Kar N. , Monnens L. , van den Heuvel L.
Kidney Int.63:1995-1999(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP HIS-235; TYR-311 AND LEU-353;VARIANT LEU-457
26.

"Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13."
Pimanda J.E. , Maekawa A. , Wind T. , Paxton J. , Chesterman C.N. , Hogg P.J.
Blood103:627-629(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP ILE-196;VARIANT GLU-448
27.

"Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome."
Matsumoto M. , Kokame K. , Soejima K. , Miura M. , Hayashi S. , Fujii Y. , Iwai A. , Ito E. , Tsuji Y. , Takeda-Shitaka M. , Iwadate M. , Umeyama H. , Yagi H. , Ishizashi H. , Banno F. , Nakagaki T. , Miyata T. , Fujimura Y.
Blood103:1305-1310(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP TRP-193; PHE-673; TYR-908 AND CYS-1123;VARIANT GLU-448;CHARACTERIZATION OF VARIANTS TTP TRP-193; PHE-673; TYR-908 AND CYS-1123
28.

"Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura."
Uchida T. , Wada H. , Mizutani M. , Iwashita M. , Ishihara H. , Shibano T. , Suzuki M. , Matsubara Y. , Soejima K. , Matsumoto M. , Fujimura Y. , Ikeda Y. , Murata M.
Blood104:2081-2083(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP VAL-250;CHARACTERIZATION OF VARIANT TTP VAL-250
29.

"Ten candidate ADAMTS13 mutations in six French families with congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome)."
Veyradier A. , Lavergne J.M. , Ribba A.S. , Obert B. , Loirat C. , Meyer D. , Girma J.P.
J. Thromb. Haemost.2:424-429(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP MET-79; PRO-203; PRO-268; GLN-507; VAL-596; ARG-758 AND SER-908
30.

"Two novel ADAMTS13 gene mutations in thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome (TTP/HUS)."
Licht C. , Stapenhorst L. , Simon T. , Budde U. , Schneppenheim R. , Hoppe B.
Kidney Int.66:955-958(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP CYS-390
31.

"Identification of two novel mutations in ADAMTS13 gene in a patient with hereditary thrombotic thrombocytopenic purpura."
Liu F. , Jin J. , Dong N.Z. , Wang Y.G. , Ruan C.G.
Zhonghua Xue Ye Xue Za Zhi26:521-524(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LEU-903 AND TRP-1095
32.

"Modulation of ADAMTS13 secretion and specific activity by a combination of common amino acid polymorphisms and a missense mutation."
Plaimauer B. , Fuhrmann J. , Mohr G. , Wernhart W. , Bruno K. , Ferrari S. , Konetschny C. , Antoine G. , Rieger M. , Scheiflinger F.
Blood107:118-125(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS TRP-7; GLU-448; ALA-618 AND VAL-732;CHARACTERIZATION OF VARIANT TTP TRP-1336;DISCUSSION OF MUTUAL MODULATORY EFFECTS OF POLYMORPHISMS
33.

"Mechanisms of the interaction between two ADAMTS13 gene mutations leading to severe deficiency of enzymatic activity."
Peyvandi F. , Lavoretano S. , Palla R. , Valsecchi C. , Merati G. , De Cristofaro R. , Rossi E. , Mannuccio Mannucci P.
Hum. Mutat.27:330-336(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP MET-88 AND VAL-1239;CHARACTERIZATION OF VARIANTS TTP MET-88 AND VAL-1239
34.

"Novel ADAMTS-13 mutations in an adult with delayed onset thrombotic thrombocytopenic purpura."
Tao Z. , Anthony K. , Peng Y. , Choi H. , Nolasco L. , Rice L. , Moake J.L. , Dong J.F.
J. Thromb. Haemost.4:1931-1935(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP TRP-1060;CHARACTERIZATION OF VARIANTS TTP TRP-1060
35.

"Novel compound heterozygote mutations (H234Q/R1206X) of the ADAMTS13 gene in an adult patient with Upshaw-Schulman syndrome showing predominant episodes of repeated acute renal failure."
Shibagaki Y. , Matsumoto M. , Kokame K. , Ohba S. , Miyata T. , Fujimura Y. , Fujita T.
Nephrol. Dial. Transplant.21:1289-1292(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP GLN-234;VARIANT LEU-903
36.

"A common origin of the 4143insA ADAMTS13 mutation."
Schneppenheim R. , Kremer Hovinga J.A. , Becker T. , Budde U. , Karpman D. , Brockhaus W. , Hrachovinova I. , Korczowski B. , Oyen F. , Rittich S. , von Rosen J. , Tjonnfjord G.E. , Pimanda J.E. , Wienker T.F. , Lammle B.
Thromb. Haemost.96:3-6(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP ILE-196; CYS-263; SER-347; LEU-353; GLN-507; LEU-671 AND TRP-1060
37.

"In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura."
Donadelli R. , Banterla F. , Galbusera M. , Capoferri C. , Bucchioni S. , Gastoldi S. , Nosari S. , Monteferrante G. , Ruggeri Z.M. , Bresin E. , Scheiflinger F. , Rossi E. , Martinez C. , Coppo R. , Remuzzi G. , Noris M.
Thromb. Haemost.96:454-464(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP TRP-1060; CYS-1123 AND TRP-1219;CHARACTERIZATION OF VARIANTS TTP TRP-1060; CYS-1123 AND TRP-1219;VARIANT GLU-448
38.

"A first case of congenital TTP on the African continent due to a new homozygous mutation in the catalytic domain of ADAMTS13."
Meyer S.C. , Jeddi R. , Meddeb B. , Gouider E. , Lammle B. , Kremer Hovinga J.A.
Ann. Hematol.87:663-666(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP PHE-119
39.

"Pregnancy-induced thrombocytopenia and TTP, and the risk of fetal death, in Upshaw-Schulman syndrome: a series of 15 pregnancies in 9 genotyped patients."
Fujimura Y. , Matsumoto M. , Kokame K. , Isonishi A. , Soejima K. , Akiyama N. , Tomiyama J. , Natori K. , Kuranishi Y. , Imamura Y. , Inoue N. , Higasa S. , Seike M. , Kozuka T. , Hara M. , Wada H. , Murata M. , Ikeda Y. , more...
Br. J. Haematol.144:742-754(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TTP THR-178; TRP-193; CYS-304; CYS-349; ASP-525 AND PRO-606;VARIANTS ARG-339; GLU-448 AND ALA-618
40.

"The first deletion mutation in the TSP1-6 repeat domain of ADAMTS13 in a family with inherited thrombotic thrombocytopenic purpura."
Palla R. , Lavoretano S. , Lombardi R. , Garagiola I. , Karimi M. , Afrasiabi A. , Ramzi M. , De Cristofaro R. , Peyvandi F.
Haematologica94:289-293(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP 977-CYS--ARG-979 DELINS TRP
41.

"A novel homozygous missense ADAMTS13 mutation Y658C in a patient with recurrent thrombotic thrombocytopenic purpura."
Lee S.H. , Park J.H. , Park S.K. , Lee E.H. , Choi J.I. , Visentin G.P. , Park T.S. , Oh S.H. , Kim S.R.
Ann. Clin. Lab. Sci.41:273-276(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TTP CYS-658
42.

"ADAMTS13 gene mutations in children with hemolytic uremic syndrome."
Choi H.S. , Cheong H.I. , Kim N.K. , Oh D. , Park H.W.
Yonsei Med. J.52:530-534(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LEU-1314

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